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On the internet I am known as Slip. I am a 22 year old nerdface who practically lives and breathes laboratory medicine.

This blog has a No Live Tissue policy in regards to its images. In addition, the views in this blog do not necessarily reflect those of my employers.
Lab Tests

Onion bulb structures, toluidine blue stain.

Hypertrophic changes with onion-bulb formation occur most commonly as a result of recurrent segmental demyelination and are most often seen in hereditary neuropathies (such as the fairly common Charcot-Marie-Tooth disease). The schwann cell doesn’t wrap around the axon properly and as a result, you get these strange involutions in the histological section.

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